Update (8-31-2018): We have someone currently in the process of testing our Peptiva.

Note:  This is just a review.  Click Here to visit the official Peptiva website.

Contents

What is Peptiva
Peptiva Reviews
Who Makes Peptiva
Who is Dr. David Katz
Where else can you buy it
Conclusion

Scrolling through my yahoo news feed earlier this morning, I came across a sponsored post that stated to “Take 1 before bed, wake up rested and less bloated”.

I never really wake up “bloated”, but there are some mornings where the fog just never seems to lift.

I wouldn’t mind waking up more rested, especially after a night of binge watching House of Cards on Netflix.

Additionally, I haven’t been feeling my usual, energetic self lately.

Because of that and wanting to get myself back to normal, I was intrigued and had to take a little deeper of a look.

Clicking on the ad, I was taken to a sponsored post that talked about the importance of your gut on maintaining a healthy body.

The supplement in question was a probiotic pill called Peptiva.

It was clearly labeled as an advertisement, but the ad copy left me intrigued.

Could my recent lack of energy be attributed to my poor gut health?

I’m not going to lie, I don’t have a TON of experience with probiotic pills.

I’ve only tested a handful of them, including Bio X4, and I’ve done a bit of research on the various probiotic pills that are sold in stores like GNC, Walmart, Walgreens, and CVS.

I also understand why they may (or may NOT) be helpful in improving your digestive system, and my wife seems to swear by them.

Let’s see what Peptiva has to say about the matter.

1.  What is Peptiva?

Note:  I was recently contacted by one of the founders of Peptiva, Brandon Adcock.

He wanted to share some info about Peptiva in regards to how it was formulated and why it costs what it does.

It’s actually a really interesting and insightful look into the “backstory” of how supplements like this are developed, check it out below:

“The project started as a blank slate for Dr. Katz to create the optimal probiotic.  His thesis boils down to everyone is taking probiotics at the wrong time.

They’re taking them in the morning then dumping junk food, soda, stresses of the day, and everything else into their system which isn’t creating the optimal environment for the probiotic to work.  So after further research, we found that one of the most common reasons people have trouble sleeping is because gut and intestinal issues.

Two of the most common items purchased at GNC with probiotics are melatonin and stress relief ingredients.

We decided that people didn’t even realize the connection and we need to pair the 2 together.

By combining the two, we can ensure the consumer is put into a restful state to create the optimal environment for the probiotic to work.  The byproduct of this is that you also get a great night’s sleep.

The product made an in ultra-high end facility in the UK that uses a patented freeze drying process to lock in the stability of the probiotics.

Most probiotics labels their CFU count as “time of manufacturing”, which essentially means that when you buy it there is no guarantee about what you’re going to get.

On top of the sleep angle and that we’re using clinically studied probiotic strains at the specific clinically studied dose, we guarantee a CFU count, at the time of expiration (18 months), even at room temperature storage.

This requires a lot more investment and drives up the price of the product.  If you look at all of the large low cost probiotic brands, they are all labeled as “time of manufacturing”.

We don’t believe in this want to guarantee a standard that our customer will get.   Based on storage, timing, and heat conditions, those probiotics may only have 10% of label claim left when a customer buys them.

This a huge problem with probiotics that most consumers don’t understand.”

According to their official website (www.peptivaprobiotics.com), Peptiva is a multi-strain probiotic matrix that is designed to help:

• Renew digestive health
• Target digestive discomfort at the source
• Restore balance as you sleep

It was apparently developed by Dr. David L. Katz, a director and co-founder of the Yale preventative research center, and director of integrative medicine at griffin hospital, located in Shelton, Connecticut.

Peptiva is designed to be taken at night, and is formulated with the following ingredients:

2.  Proprietary Priobitic Matrix (26 billion cfu)

• Lab4 Clinical Cultures:  Lactobacillus acidophilus (ATCC SD6865), Lactobacillus acidophilus (ATCC SD6866), Bifidobacterium bifidum (ATCC SD6869), Bifidobacterium animalis subsp. lactis (ATCC SD6870)
• Active microbiome blend: Lactobacillus rhamnosus IMC501, Lactobacillus paracasei IMC502
• GABA
• Valerian Root Extract
• Melatonin (immediate release)
• Melatonin (delayed release)

From my perspective, this looks like a decent formula.

Here’s a snapshot of the Peptiva label:

It definitely contains a suitable amount of probiotics to get the job done, and the addition of the sleep aids is definitely a plus.

I also like the fact that Peptiva is not pumping a HUGE amount of those sleep aids into their formula.

There’s a lot of sleep aids out there that will put anywhere from 2 to as much as 8 mg of melatonin into their supplements, which is WAY more than the recommended dose.

Too much melatonin like this has a tendency to disrupt your sleep cycle, and can often leave you feeling groggy the next day.  (Source)

Peptiva only contains a total of 1.5 mg of melatonin, so you should be safe in that regard.

The only Peptiva side effects you may encounter would be the same ones you would get with just about any probiotic.  (Source)

This includes digestive issues like gas, constipation, irritable bowel syndrome, diarrhea, bloating, and nausea.

These tend to be mild in nature (if at ALL), and in most cases is a sign that the product may actually be working.

Our Personal Results

We sent a free box of Peptiva to one of our site visitors via our STEPuP program.  Her name is Laci L., and she has been putting together her thoughts on the product so far.

Follow along on her diary below:

First use: 9/3/18

To start, I am a 23-year-old female who suffers from both IBS (irritable bowel syndrome) and insomnia. As many knows, IBS is different for different sufferers. My problem is that I CANNOT go, often 2-3 days at a time without relief. Certain foods, such as dairy, and others that I’m still trying to identify, cause severe bloating/gas/abdominal pain. There are many nights that my body needs to go, I’m in pain after a few days’ worths of meals sitting in my stomach, and I cannot go. My doctor has suggested I use various things to treat it, but unfortunately, there is no one solution to IBS, it is trial and error. In the past few months, I have started using a probiotic (I won’t name here), and it helped with my symptoms. I was then given Peptiva for a trial run and stopped using my previous probiotic for about five days.

My insomnia prevents me from getting a full night of sleep. Falling asleep is usually not a problem for me, taking me anywhere from 10-30 minutes depending on the night. Note – I am training for a half marathon, so I am getting extreme exercise in most days, which helps with falling asleep. But I wake up twice a night consistently but can fall back asleep quickly. I wear a Garmin watch that tracks my sleep, and it shows I am barely getting 30 minutes of deep sleep per night. I was excited to use Peptiva as a sleeping aid.

9/5

The past two nights I have used the product, and I haven’t noticed a drastic change, but it is very early. I am not falling asleep any quicker or noticing that I am “going” more in the bathroom. But I am not suffering from any gas/bloating/abdominal pain anymore. That could be related.

9/7

I have finally noticed the effects of the sleeping aid. It isn’t rare for me to ignore my sleepiness, as I am a night owl. Many nights I want to clean up my room or scroll through my phone. For me, Peptiva is NOT forcing me to go to bed. I never feel my body being so tired, even 30 minutes after taking it that I have to fall asleep. But I do notice myself getting a bit more tired. The biggest effect is that my body/mind feel very heavy after taking it. When I am in a bed, usually 30 minutes after I have taken it, I feel like my body is wanting to fall into a very deep sleep. I’m not sure how to explain the sensation, but I feel heavy. I like it this feeling! A positive for me.

9/11

I have been using the probiotic for a week now. I forgot to take it one night over the weekend, and I noticed I wasn’t as regular. I like the product, but I’m not sure if I would buy this again considering the price. It is a good sleep aid, but not significantly better than regular melatonin that I get from CVS for less than $10. The steep price is not worth it for being a slightly better sleep aid than natural supplements.

As for the probiotic, I have noticed a positive difference in my body. I am not experiencing as many IBS symptoms, which I believe is attributed to this product and healthier eating on my part. This product helps with stomach problems and does what it claims. But before I started this product, I was using a probiotic that was more reasonably priced, and I believe it worked better than Peptiva. With my previous probiotic, I noticed myself going to the bathroom immediately after work, which is relieving myself after two full meals (breakfast and lunch). This is not normal for me, as sometimes I can have 6+ meals in my stomach before I can go. With the last probiotic, I even went to the bathroom at work, which NEVER happens to me. Peptiva did not provide the same drastic results. Using Peptiva I still go the bathroom every single day, but it is not immediately after work. It is sometimes after I’ve had my third meal for the day.

Week 1 – Do I recommend the product?

Yes, I do. It does what it claims, but I don’t think it is the best product on the market. It helps me fall asleep a bit quicker, in a natural way. I like it because it doesn’t feel like I’m taking a prescription sleep aid that knocks you out (and is addictive). My Garmin watch is also reporting a small increase in my deep sleep for the week. When I remember to take melatonin, I usually get similar results, but maybe a little less than when I use Peptiva.

The product successful does what it claims as probiotic. I assume it is doing all of the right things on the inside, helping with good gut bacteria, etc. I’m just not sure it is worth the steep price.

Week 1 – Would I buy again?

No, I think I can get similar if not better results for cheaper.

Week 2 – 9/17

CON: Something that I didn’t think of before that really annoys me about this product, that I also love about this product, is that it is a sleep aid. Obviously, it is great to have this product at night to help me sleep! But on the other hand, you cannot take this at any other time of the day. I used to have great results awhile back taking a probiotic on an empty stomach right when I woke up. It really kick started my system. Sometimes after a big meal and I’m feeling overly full, I want to pop a probiotic. You can’t do that with Peptiva, it is exclusively for night time use. Sometimes I want to use a probiotic in the morning AND at night, and I can’t do that with this product, which is frustrating for me.

I have been taking the product for a few weeks now. So far, so good! My digestion seems to be improving, and I notice I really am not suffering from bloating from most meals anymore. Before I started using this product I had bloating or gas at least once a day from a meal. When I do experience discomfort after a meal I am now able to determine which food is causing the upset. I really think Peptiva has been helping with the bacteria in my gut and is doing more for me than just making it easier to fall asleep at night.

Visit The Official Peptiva Site Here: www.Peptiva.com

As the product has built in my system I’ve noticed it working even better than at the beginning. Two weeks in and I am experiencing less disrupted sleep than before. At this point, I’m not sure if melatonin provided as much sleep aid as Peptiva. Last week I argued that this is a glorified melatonin, but I’m starting to think I was wrong. Stay tuned.

2 weeks in, I really like the product. If you are wanting a good probiotic to improve your gut and quality of sleep, and the price is not an issue for you, then this product is for you.

If you are on a tighter continue reading:

• The product is expensive. There is no denying it. But to get the same results (probiotic and sleep aid) you will need to purchase two products. This is a two-in-one deal, which is less work on your end.

• If you find a cheaper probiotic that does the same job, then yay! You saved some money. But if you are also wanting the sleep aid component, calculate the cost of a comparable sleep aid.

• This is a safe, non-addictive product that helps you sleep, keep that in mind when you shop around for alternatives.

Again – if you are on a budget like myself, I don’t have an answer for you yet. For simplicity, it may be worth the money because it does provide results and is just one product to take every night.

3.  Peptiva Reviews

This is where things start to turn a bit south.

Apart from their website, the only independent Peptiva reviews I could find were on Amazon, where it was rated an average of 2.2 out of 5 stars.

Other than a couple of people that noted some positive results, the vast majority were complaining about the price.

And at almost $60 for a 30 capsule bottle, I sort of have to agree with them.

If you run a search for probiotic pills on Amazon, you’ll see that the vast majority are priced in the $10 – $25 range.

It is ultimately up to you to decide if the potential positive effects and results that it can have on your life are worth the hefty price tag, or if you would rather take a lot at some of the less expensive competitors.

At $60 per box, you’re looking at a 42% – 160% between Peptiva and most other Probiotic pills.

I can understand their angle.

Most of these probiotic supplements are literally just that…probiotics.

They don’t include additional ingredients like melatonin, GABA, and Valerian root.

However, Peptiva does.

Does that justify such a huge price increase?

That’s up to the individual to make that decision, but based on the reviews I’m seeing here, they may have priced themselves out of the market on Amazon.

4.  Who Makes Peptiva?

According to my research, Peptiva is owned by a private company called Direct Digital LLC. They were founded by Brandon Adcock and Paul Reichelt, and Dr. David L. Katz was brought on recently as their chief scientific advisor (more on him below).

Their official website is the following:  www.PeptivaProbiotics.com

This company is behind many other popular supplement brands such as Nugenix, Instaflex, and Lumiday, all of which we have personally tested.

5.  Who is Dr. David Katz?

According to Wikipedia, Dr. David Katz was born on Feb. 20, 1963 in Los Angeles, California, and he is a physician and founding director of the Yale-Griffin Prevention Research Center.

He earned his B.A. degree from Dartmouth College, his M.D. from Albert Einstein College of medicine, and his MPH from Yale Univ. School of Public Health.

According to his website, he has published roughly 200 research scientific articles, as well as 15 books.

The most notable of these is “Disease Proof:  Slash Your Risk Of Heart Disease, Cancer, Diabetes, and More – By 80 Percent”, which as of this review had 125 reviews on Amazon.

Here are a few quotes from Dr. Katz regarding the importance of probiotics:

“The natural way to get ‘probiotics’ would be exposure throughout the day.  They would enter through the mouth all during the day, and likely settle into the large bowel during the night, and colonize then.  By providing a concentrated dose of commensal bacteria at night, we are attempting to reproduce this native pattern.

Also, during the day, a probiotic supplement will be affected by changes in movement through the GI tract at different times, with variations induced by food intake.  During the night, there is a relatively constant state of GI muscle activity (peristalsis), and thus a stable environment for bacterial colonization.

Fundamentally, the human body replenishes itself in sleep.  This is the logical time to replenish the microbiome, without sudden changes in insulin levels, stress hormones, digestive activity.  Probiotic bacteria encounter a gut mucosa at relative rest, in its own ‘replenishment’ mode, and can populate the mucosa accordingly.”

6.  Where else can you buy it?

Apart from Amazon, you can find Peptiva both on their website, www.peptivaprobiotics.com, as well as GNC.

They also offer a 15 day trial here.

Related Article:  How To Cancel A Supplement Free Trial (and get your money back)

Your best bet, from a cost perspective, is to buy it on their official site.

At GNC (just like Amazon), it costs $60 for a box of 30 capsules.

On their website, that very same bottle is sold at the same price.

HOWEVER, Peptiva does offer a substantial discount if you purchase more than one box.

For example, if you buy 2, you get 1 free.  This brings the price down to an average of $49.99 per box.

If you buy 3, you’ll actually get 2 free.  This brings the price down to an average of $44.99 per box, making it even cheaper.

However, this is NOT what’s reflected when you go to checkout.

For example, we’ve already established that a one month supply of Peptiva costs $60.

When you select the “Buy 2 Get 1 Free” deal, that should come out to a total of $120, right?

Well, when I did that this is what shows up:

The same thing happens when you select the “Buy 3 Get 2 Free” deal.  Based on the one month supply pricing, it should come out to $180 (3 Boxes X $60 a box = $180).

And this is what ends up showing up:

I may have to shoot them a message and let them know this pricing is way out of wack.

7.  Conclusion

Peptiva certainly does a good job at differentiating themselves from other supplements in this category.

It was developed by a doctor, so you KNOW it will contain what they say it contains.

It contains more than just a simple probiotic formula.

It’s sold at GNC.

But does the high price justify all of this.

The only other thing I wanted to mention was that they are currently offering samples for their product.

This might actually be the way to go, given the big initial price tag.

One thing I would caution you on is that it’s really not just a “sample”.

It’s a trial, which basically means that you will have 18 days to try the product out.

If you do nothing, they will charge you the full price for the product ($59.99).

It’s all right here in the terms and conditions:

Cancelling is easy, all you have to do is email them at support@peptivaprobiotics.com or call their customer support phone number at 800-355-6050 and tell them you’d like to stop the trial.

Again, this may be the better route to take so that you can accurately judge whether or not the supplement is right for you, without having to fork over a significant amount of cash upfront.

We’ll be testing this supplement soon, so stay tuned.

Have You Used Peptiva?  Leave Your Review Below!

Ask A Question

User Questions and Answers

Can Peptiva be taken if you have heart issues like heart failure and taking heart meds? -Lee

Because of your medical condition, you'll need to check with your doctor to be sure any supplement is safe for you to take.- Rob

Can I take 2 tablets of Peptiva? One tablet didn't help. Does it take a while for it to work? I didn't get any sleep when took one pill. -Gary

There is no warning against taking more than the recommended dose, so you'll probably be fine taking 2. I wouldn't go any higher than that.- Rob

How do I cancel the subscription to Peptiva? -John

Call the company you ordered from and let them know you want to cancel your subscription. If you're having trouble finding their number, check the transaction on your credit card. There's a good chance it's listed there.- Rob

Peptiva does work for me. I am able to relax get a good night's rest without feeling groggy in the morning. I had trouble sleeping before. I do seem to notice a slight improvement with bloating as well. Is this product tested by the FDA? -Kim

As a supplement, Peptiva does not need or even qualify for FDA testing or approval.- Rob

Does Peptiva interact with any med's, and would any of the ingredients interfere with heart palpitations? -Ina

These are questions for your doctor. I don't have the knowledge of pharmaceuticals or medical conditions to know what's safe to use with each.- Rob

I took Peptiva for the second time last night. I have been having constipation issues for a while off and on. Peptiva worked after the first night, but today I have had a sour stomach and in the bathroom about 6-8 times. Not diarrhea but frequent. Could this be a side affect, and will it go away? -Gail

Gastrointestinal issues are included in the possible side effects, but hang in there. They do go away.- Rob

what is gaba and why it is in this. Is it a derivative of gabapentin, which is a dangerous drug and not a probiotic. I cannot take melatonin it causes me problems why put these things in a probiotic -Roselynn

GABA )Gamma Amino-Butyric Acid is a chemical made in the brain. It's often included in supplements to relieve anxiety, improve mood, and promote lean muscle growth and retention. It's chemically related to Gabapentin but it's more similar to the chemical made in the brain.- Rob

Dose Peptiva help you lose weight? -Shelia

Along with a good diet and exercise, Peptiva can indeed help you lose weight in two ways. It can help get your gut in order to work for you instead of against you, and it can help you get the sleep you need to lose and maintain a healthy weight.- Rob

How does peptiva make you sleep better? -Pamela

The GABA, Valerian, and Melatonin are the ingredients that help you sleep.- Rob

Is it normal to change your boob color ?off white? -Cindy reed

I have not heard of this as a side effect.- Rob

Who has the cheapest price? -suzanne

Amazon and the website each have the same price. You may be able to look around and find a better price, but I'm not aware of any.- Rob

I just received my bank statement and Peptiva submitted $59.00 without my approval. I signed for the free trial not the 1 month supply whic I never received. Kindly credit my account for the unauthorized amount of $59.00. -Inez

SupplementCritique.com is a review website. We have no relationship with Peptiva. You'll need to contact them directly to address your issue. The customer service phone number listed on their website is 1-800-355-6050.- Rob

Is this good for men -John

It is recommended for both men and women.- Rob

I took my first pill last night a hour before I went to bed I slept okay but once I woke up I have been running to the bathroom is this normal and will it stop -Wendy

Though not typical, I have seen a few reviewers mention stomach aches and diarrhea. I'm not sure how long it tends to last. I'd give it a few days, and discontinue use if it doesn't stop.- Rob

I received the product two weeks after the trail purchase . I took the first one upon receipt of the product . A day later one side of my face was covered with a rash . The second day , my left of my throat hurt . On the third day , my left jawbone had a huge knot on it . Is this a common reaction ? -Sherion

No, not common at all. In fact, I've never heard of these issues with Peptiva. If I were you, I'd discontinue use.- Rob

Does this product help someone that has had a gastric bypass? Such as the bloating and restroom issues. Do not have constipation? -LeeAnn

Because gastric bypass is a medical procedure, you'll need to talk to your doctor about what medicines or supplements may help with related issues.- Rob

Author: Rob Miller

Rob Miller founded SupplementCritique.com over 7 years ago, and has been the chief editor ever since. He has a diploma in Advanced Dietary Supplements Advisor, and worked at GNC for 3 years. He KNOWS supplements, both inside and out. Rob currently resides in Jupiter, FL, with his wife of 4 years.  Learn more about him in his Bio here. Follow him on Twitter , Facebook, LinkedIn, or find him on Google +. View all posts by Rob Miller